Search on: ADMINISTRATION, TOPICAL 
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Descriptor English:   Administration, Topical 
Descriptor Spanish:   Administración Tópica 
Descriptor Portuguese:   Administração Tópica 
Synonyms English:   Drug Administration, Topical  
Tree Number:   E02.319.267.120
Definition English:   The application of drug preparations to the surfaces of the body, especially the skin (ADMINISTRATION, CUTANEOUS) or mucous membranes. This method of treatment is used to avoid systemic side effects when high doses are required at a localized area or as an alternative systemic administration route, to avoid hepatic processing for example. 
Indexing Annotation English:   general; prefer specifics; "topical" in titles frequently means ADMINISTRATION, CUTANEOUS
History Note English:   74 
Record Number:   287 
Unique Identifier:   D000287 

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